Genosys is dedicated to the research and development of visualization and automated analysis of high-throughput sequencing data. We develop Mendel Analytics, the world's first local sever based visualization and automated computational analysis software system for NGS, PacBio and ONT high-throughput sequencing data. The software is equipped with more than 200 popular open-source tools, databases and common workflows templates such as variant calling, RNA-Seq, LncRNA, small RNA, ChIP-Seq, 16S/18S amplicon and metagenome assembly, which facilitate the comprehensive analysis of human, plant & animal and microbial genome.
The core members of the company's research and development team are from BGI, Microsoft and Tencent. They are experts in bioinformatics analysis, automated software development and design of user interface, with an average of 9 years experience. Members who are responsible for the development of tools and workflows have published more than 20 articles in international renown scientific journals such as Science, Nature, and Nature Genetics.
Genosys' customers include some of the top universities, research institutions and hospitals around the world, such as the National University of Singapore, Temasek Life Sciences Laboratory, National University Hospital, Nanyang Technological University, Chinese Academy of Sciences, Chinese Academy of Agricultural Sciences and Zhejiang University.
[1] Hu Y,… , Niu Y, …, et al. Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton. Nature Genetics 2019, s41588-019-0371-5 (IF=32.19)
[2] Wang W, … , Niu Y, …, et al. Genomic variation in 3,010 diverse accessions of Asian cultivated rice. Nature 2018, 557(7703):43-49. (IF=41.577)
[3] Song X, Huang F…, et al. Genome-wide DNA methylomes from discrete developmental stages reveal the predominance of non-CpG methylation in Tribolium castaneum. DNA Research. (2017). 24(5):445-457. (IF=5.415)
[4] Zhang D, Li W, … , Niu Y, …, et al. The medicinal herb Panax notoginseng genome provides insights into ginsenoside biosynthesis and genome evolution. Molecular Plant, 2017, 10(6): 903-907.(IF=8.8)
[5] Yin W, Wang Z, … , Lian J, …, et al. Evolutionary trajectories of snake genes and genomes revealed by comparative analyses of five-pacer viper. Nature Communications, 2016, 7: 13107.(IF=12.12)
[6] Zhao J, ... , Zou L, ..., et al. Transcriptome and proteome analyses reveal complex mechanisms of reproductive diapause in the two-spotted spider mite, Tetranychus urticae. Insect Molecular Biology, 2016. doi:10.1111/imb.12286. (IF=2.492)
[7] Yang R, Huang F, ..., et al. Differential transcription profiles of long non-coding RNAs in primary human brain microvascular endothelial cells in response to meningitic Escherichia coli. Scientific Reports, (2016) doi:10.1038/srep38903.(IF=4.122)
[8] Tribolet L, Cantacessi C, ..., Huang F, et al. Probing of a Human Proteome Microarray With a Recombinant Pathogen Protein Reveals a Novel Mechanism by Which Hookworms Suppress B-Cell Receptor Signaling. Journal of Infectious Diseases 2015; 211(3):416-425. (IF=6.344)
[9] Shao C, Niu Y, Rastas P, et al. Genome-wide SNP identification for the construction of a high-resolution genetic map of Japanese flounder (Paralichthys olivaceus): applications to QTL mapping of Vibrio anguillarum disease resistance and comparative genomic analysis. DNA Research 2015; 22(2): 161-170. (IF=5.267)
[10] Liu H, Niu Y, Gonzalez-Portilla PJ. et al. An ultra-high-density map as a community resource for discerning the genetic basis of quantitative traits in maize. BMC Genomics. 2015, 16:1078 (IF=3.867)
[11] Li F, Xiao Y, Huang F, et al. Spatiotemporal-specific lncRNAs in brain, colon, liver and lung of macaque during development. Molecular Biosystems, 2015, 11. (IF=2.829)
[12] Kang L, Huang F, ..., et al. Transcription Analysis of the Beta-Glucosidase Precursor in Wild-Type and l-4i Mutant Bombyx mori(Lepidoptera: Bombycidae). Journal of Insect Science 2015, 15(1): 79. (IF=0.650)
[13] Zhang G, Li Q, … , Lian J, …, et al. Comparative genomics reveals insights into avian genome evolution and adaptation. Science 2014, 346(6215): 1311-1320. (IF=34.611)
[14] Chen S, Zhang G, … , Lian J, …, et al. Whole-genome sequence of a flatfish provides insights into ZWsex chromosome evolution and adaptation to a benthic lifestyle. Nature Genetics 2014, 46(3):253-60. (IF=32.19)
[15] Shao C, Li Q, … , Lian J, …, et al. Epigenetic modification and inheritance in sexual reversal of fish. Genome Research 2014, 24(4):604-15. (IF=11.351)
[16] Wang X, Fang X, … , Lian J, …, et al. The locust genome provides insight into swarm formation and long- distance flight. Nature Communications 2014, 5:2957.(IF=11.329)
[17] Li Q, Wang Z, Lian J, Nygaard S, …, et al. Caste-specific RNA editomes in the leaf-cutting antAcromyrmex echinatior. Nature Communications 2014, 5: 4943. (IF=11.329)
[18] Qin C, Yu C, Shen Y, ..., Niu Y , ..., et al. Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. Proceedings of the National Academy of Sciences 2014; 111(14): 5135-5140. (IF= 9.423)
[19] Jacobsen MW, Pujolar JM, ..., Niu Y, et al. Genomic footprints of speciation in Atlantic eels (Anguilla anguilla and A. rostrata). Molecular Ecology 2014, 23:4785-4798. (IF=5.947)
[20] Yan L, Wang X, … , Lian J, …, et al. The Genome of Dendrobium officinale Illuminates the Biology of the Important Traditional Chinese Orchid Herb. Molecular Plant 2014, 8(6):922-34. (IF=7.142)
[21] Ferchaud A, …, Niu Y, …et al. A low-density SNP array for analyzing differential selection in freshwater and marine populations of threespine stickleback (Gasterosteus aculeatus) BMC Genomics 2014, 15:867 (IF=3.867)
[22] Wang X, Li Q, Lian J, Li L, …, et al. Genome-wide and single-base resolution DNA methylomes of the Pacific oyster Crassostrea gigas provide insight into the evolution of invertebrate CpG methylation. BMC Genomics 2014, 15(1):1119. (IF=3.867)
[23] LI Z, ... , Niu Y , ..., et al. The 3000 rice genomes project. GigaScience 2014; 3:7 doi:10.1186/2047-217X-3-7. (IF=7.463)
[24] Xiang H , …Lian J, …, et al. Comparative methylomics between domesticated and wild silkworms implies possible epigenetic influences on silkworm domestication. BMC Genomics 2013, 14(1): 646. (IF=3.867)
[25] Bonasio R, Li Q, Lian J, …, et al. Genome-wide and Caste-Specific DNA Methylomes of the Ants Camponotus floridanus and Harpegnathos saltator. Current Biology 2012,22(19): 1755-1764. (IF=8.983)
Genosys Inc./Total Genomics Solution Pte. Ltd.
Address: 21 Bukit Batok Crescent, #17-82 Wcega Tower, Singapore 658065
E-mail: tech@genosys-us.com
Tel: 65 6225 5788